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产品概述
产品信息
| 别名 | Interleukin-18 Receptor accessory Protein (IL18RAP); Accessory Protein-like; CD218 antigen-like family member B; CDw218b; IL-1R accessory Protein-like; Interleukin-1 Receptor 7; Interleukin-18 Receptor accessory Protein-like; Interleukin-18 Receptor |
| 物种 | Human |
| 表达宿主 | Human Cells |
| 序列信息 | Phe20-Arg356 |
| 检索号 | O95256 |
| 分子量 | 39.4 kDa |
| 表观分子量 | 56 kDa |
| 标签 | C-6His |
产品特性
| 纯度 | >95% as determined by reducing SDS-PAGE. |
| 内毒素 | < 1.0 EU per µg as determined by LAL test. |
| 保存 | Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months. |
| 运输 | Ambient temperature or ice pack. |
| 制剂 | Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
| 复融 | Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
背景介绍
IL-18RAP is a single-pass type I membrane Protein and contains two Ig-like C2-type domains and one TIR domain, IL18RAP can be induced by IFN-alpha and IL12 in nature killer cells and T-cells. The coexpression of IL18R1 and IL18RAP is required for the activation of NF-kappa B and JNK in response to IL-18.Defects in IL18RAP are associated with Coeliac disease.
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