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产品概述
产品信息
| 别名 | Fibroblast Growth Factor 7; FGF-7; Heparin-binding Growth Factor 7; HBGF-7; Keratinocyte Growth Factor; FGF7 |
| 物种 | Human |
| 表达宿主 | Human Cells |
| 序列信息 | Cys32-Thr194 |
| 检索号 | P21781 |
| 分子量 | 20.0 kDa |
| 表观分子量 | 20-27 kDa |
| 标签 | C-6His |
| 生物活性 | Measured in a cell proliferation assay using HaCaT cells. The ED50 for this effect is 10.94 ng/ml. |
产品特性
| 纯度 | >95% as determined by reducing SDS-PAGE. |
| 内毒素 | < 1.0 EU per µg as determined by LAL test. |
| 保存 | Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months. |
| 运输 | Ambient temperature or ice pack. |
| 制剂 | Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
| 复融 | Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
背景介绍
Fibroblast Growth Factor 7 (FGF7) is a secreted Protein which is mainly located in epithelial cells and belongs to the heparin-binding Growth Factors family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF7 is a potent epithelial cell-specific Growth Factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. It is possible major paracrine effector of normal epithelial cell proliferation.
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