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产品概述
| 名称 | RSC96 (大鼠雪旺细胞) (种属鉴定正确) |
| 别称 | RSC 96; RSC-96 |
| 种属 | 大鼠 |
| 生长特性 | 贴壁细胞 |
| 细胞形态 | 神经细胞样 |
| 冻存条件 | 冻存液：55% 基础培养基+40%FBS+5%DMSO 温度：液氮 |
| 培养方案A（默认） |
培养条件:
气相：空气，95%；CO2，5%, 温度：37℃
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| 推荐传代比例 | 1:3-1:4 |
| 推荐换液频率 | 2-3次/周 |
| 背景描述 | RSC96细胞是原代培养的大鼠雪旺细胞经长时间培养后自发转化而成的。2002年12月提交到ATCC的RSC96细胞污染了支原体，RSC96细胞后代细胞通过BM细胞周期蛋白处理21天消除支原体。处理后6周，用Hoechst染色、PCR和标准培养测试进行支原体检测，结果都呈阴性。 |
| 组织来源 | 雪旺细胞 |
| 细胞类型 | 自发永生化细胞 |
| 生物安全等级 | BSL-1 |
| 受体表达情况 | Nerve growth factor receptor (Ngfr); Protein and mRNA, negative;Platelet derived growth factor receptor, alpha; negative;Platelet derived growth factor receptor, beta; negative |
| 保藏机构 | ATCC; CRL-2765 |
种属鉴定
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种属鉴定图
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参考文献
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Endothelial cell-derived exosomes boost and maintain repair-related phenotypes of Schwann cells via miR199-5p to promote nerve regeneration(2023/01/09)
作者：Jinsheng Huang, Geyi Zhang, Senrui Li
期刊：JOURNAL OF NANOBIOTECHNOLOGY
DOI：10.1186/s12951-023-01767-9
影响因子 ：10.200
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Endogenous Electric Field-Coupled PD@BP Biomimetic Periosteum Promotes Bone Regeneration through Sensory Nerve via Fanconi Anemia Signaling Pathway(2023/01/27)
作者：Yanlin Su, Lian Zeng, Rongli Deng
期刊：Advanced Healthcare Materials
影响因子 ：10.000
引用产品：CL-0199
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Aptamer engineering exosomes loaded on biomimetic periosteum to promote angiogenesis and bone regeneration by targeting injured nerves via JNK3 MAPK pathway(2022/09/20)
作者：Yanlin Su, Qing Gao, Rongli Deng
期刊：Materials Today Bio
DOI：10.1016/j.mtbio.2022.100434
影响因子 ：8.200
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Honokiol attenuates high glucose-induced peripheral neuropathy via inhibiting ferroptosis and activating AMPK/SIRT1/PGC-1ɑ pathway in Schwann cells(2023/08/14)
作者：Man Hu, Wen Jiang, Chen Ye
期刊：PHYTOTHERAPY RESEARCH
DOI：10.1002/ptr.7984
影响因子 ：7.200
引用产品：CL-0199
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Phosphorylated α-synuclein deposited in Schwann cells interacting with TLR2 mediates cell damage and induces Parkinson’s disease autonomic dysfunction(2024/01/26)
作者：Yangxia Li, Qing Tong, Ye Wang
期刊：Cell Death Discovery
DOI：10.1038/s41420-024-01824-8
影响因子 ：7.000
引用产品：CL-0199
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Cisplatin causes erectile dysfunction by decreasing endothelial and smooth muscle content and inducing cavernosal nerve senescence in rats(2023/01/25)
作者：Yinghao Yin, Yihong Zhou, Jun Zhou
期刊：Frontiers in Endocrinology
DOI：10.3389/fendo.2023.1096723
影响因子 ：5.200
引用产品：CL-0199
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Evodiamine attenuates oxidative stress and ferroptosis by inhibiting the MAPK signaling to improve bortezomib-induced peripheral neurotoxicity(2023/11/27)
作者：Yunlong Tang, Weiying Gu, Lingling Cheng
期刊：ENVIRONMENTAL TOXICOLOGY
影响因子 ：4.500
引用产品：CL-0199
