本司产品仅用于科研,不用于临床诊断和治疗

全国免费热线:400-999-2100

您身边的细胞培养专家!

所有分类
  • 所有分类
  • 细胞系
  • 原代细胞
  • 血清
  • 细胞培养基
  • 辅助试剂
  • 细胞凋亡检测试剂盒
  • 细胞房除菌产品
热搜: 胎牛血清 VERO RAW264.7 成纤维细胞 间充质干细胞 上皮细胞

忘记密码

个人邮箱:
验证码: captcha

账号激活

个人邮箱:
×
当前位置:首页 >> 产品中心 >> 辅助试剂 >> 细胞因子 >> Human

产品中心Cell Resources

联系我们CONTACT US

  • Procell-VEGF-A/ VEGF121, Human, Recombinant
  • Procell-VEGF-A/ VEGF121, Human, Recombinant

VEGF-A/ VEGF121, Human, Recombinant

货号:PCK013

价格:¥1780¥4980¥17480¥27980

规格:
10µg
  • 10µg
  • 50µg
  • 500µg
  • 1mg
数量: - +
产品概述

产品信息

别名 Vascular Endothelial Growth Factor A; VEGFA; VEGF-A; Vascular Permeability Factor; VPF; VEGF; VEGF121
物种 Human
表达宿主 E.coli
序列信息 Ala27-Arg147
检索号 P15692-9
分子量 14.2 kDa
表观分子量 16 kDa
生物活性 Immobilized Human VEGF 121 at 2μg/ml (100 μl/well) can bind Human VEGFR2-Fc.The ED50 of Human VEGFR2-Fc is 13.04 ng/ml.

产品特性

纯度 >95% as determined by reducing SDS-PAGE.
内毒素 <1.0 EU per µg as determined by LAL test.
保存 Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2~8℃ for 2~7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months.
运输 Ambient temperature or ice pack.
制剂 Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
复融 Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

背景介绍

Human VEGF121, also known as Vascular Endothelial Growth Factor A, VEGFA, Vascular Permeability Factor, VPF and VEGF, is a homodimeric, heparin-binding glyco Protein which belongs to the platelet-Derived Growth Factor (PDGF)/ vascular Endothelial Growth Factor (VEGF) family. VEGF-A is a glycosylated mitogen that specifically acts on Endothelial cells and has various effects, including mediating increased vascular Permeability, inducing angiogenesis, vasculogenesis, permeabilization of blood vessels and Endothelial cell Growth, increasing microvascular Permeability, promoting cell migration and inhibiting apoptosis. Alternatively spliced transcript variants of VEGF-A encod either secreted or cell-associated isoforms. The lymphangiogenesis may be promoted by upregulation of VEGF121, which may in turn act in part via induction of VEGF-C. It binds to the FLT1/ VEGFR1 and KDR/ VEGFR2 Receptors, heparan sulfate and heparin. NRP1/ Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor Growth.
丁莎/胡文君

丁莎/胡文君

【 上海 】

凌晶

凌晶

【 陕西 】

朱莎莉

朱莎莉

【 湖北、河南 】

刘本佳

刘本佳

【 江苏、安徽 】

章臣雄

章臣雄

【 广东、云南 】

閤春喜

閤春喜

【 四川、甘肃、西藏 】

田博浩

田博浩

【 重庆、吉林 】

石文平

石文平

【 北京、黑龙江、辽宁 】

任施博

任施博

【 江西、福建、新疆、海南 】

李荣枫

李荣枫

【 天津、河北、内蒙古、山西 】

陈雨兰

陈雨兰

【 湖南、山东、宁夏、青海 】

尹国文

尹国文

【浙江、广西、贵州】

微信扫一扫咨询

微信扫一扫咨询

在线客服
关闭
在线咨询
联系销售

关注微信公众号